Prospect Lefferts Gardens is a residential neighborhood in the Flatbush area of the New York City borough of Brooklyn. The community is bounded by Empire Boulevard (formerly Malbone Street) to the north, Clarkson Avenue to the south, New York Avenue to the east, and Ocean Avenue/Prospect Park to the west.Prospect Lefferts Gardens is part of Brooklyn Community Board 9 and is serviced by the New York City Police Department's 71st Precinct.

The neighborhood contains an ethnically diverse community with a largely Caribbean-American and African-American population. However, in recent years, Prospect Lefferts Gardens has been gentrifying quickly. Real estate development has increased and new residents from other groups have increased.